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Melatonin ameliorated blood pressure and survival in HSD. DSS Rats were treated for 9 weeks with HSD with and without melatonin. High-salt diet reduced body weight from day 36 and melatonin moderated this effect (A). HSD increased mortality rate from day 40. Treating HSD-fed rats with melatonin improve their survival. (B). (n = 8) *-p ≤ 0.05 salt and salt+melatonin versus control. #-p ≤ 0.05 salt versus control and salt+melatonin. HSD—high-salt diet.
