A, Histogram of HRD scores in the replication cohort (n=102). B, Kaplan-Meier plot of disease free survival, HRD score ≥4 vs HRD score <4. C, Kaplan-Meier plot of disease free survival in relation to MSI-positive vs MSI -negative tumors. D, Kaplan-Meier plot of disease free survival in relation to TMB-positive vs TMB-negative tumors. E, Kaplan-Meier plot of disease free survival in relation to HRD score≥4, MSI and TMB status for the entire replication cohort.