Table 2.
Parameter, Units (Reference Value) | Healthy Donors | Patients with COVID-19 | |
---|---|---|---|
Moderate (n = 18) | Severe (n = 23) | ||
Age | 37.0 (32.0;47.0) | 62.5 (52.0;70.0) ^ | 59.0 (53.0;77.0) ^ |
CT, % lung damage | 40 (32;52) * | 60 (48;68) * | |
CRP, mg/L (0–5.0) | 64.9 (39.7;80.1) | 71.4 (36.1;109.5) | |
D-dimer, µg/mL (0–5.0) | 0.55 (0.36;1.25) | 0.62 (0.40;1.48) | |
Ferritin, ng/mL (30–400) | 372.8 (148.4;901.1) | 422.6 (164.5;713.4) | |
Fibrinogen, g/L (1.9–4.3) | 6.0 (4.1;6.4) | 6.0 (4.7;7.0) | |
Troponin I, ng/mL (0–0.034) |
0.006 (0.002;0.014) | 0.002 (0.002;0.002) | |
Procalcitonin, ng/mL (0–0.5) |
0.07 (0.04;0.15) | 0.06 (0.05;0.18) | |
ALT, U/L (0–41) | 39.1 (25.2;72.1) | 29.0 (23.0;63.5) | |
AST, U/L (0–40) | 46.0 (31.0;80.0) | 37.8 (32.0;61.0) | |
LDH, U/L (135–225) | 335 (325;349) | 332 (267;410) | |
Haemoglobin, g/L | 139.5 (136.0;148.0) | 128.6 (123.0;140.3) | 141.2 (127.2;148.8) |
RBC, ×1012 | 5.00 (4.70;5.13) | 4.71 (4.07;5.02) | 4.71 (4.45;4.91) |
Ht, % | 43.2 (41.5;46.0) * | 38.6 (34.9;42.4) ^ | 40.2 (36.8;42.2) ^ |
Plt, ×109 | 208 (194;235) | 174 (153;212) | 195 (130;301) |
WBC, ×109 | 5.8 (5.4;7.7) | 5.1 (3.2;7.3) | 4.4 (3.5;6.1) ^ |
Lymphocytes, ×109 | 1.95 (1.78;2.21) * | 1.03 (0.62;1.30) ^ | 1.02 (0.75;1.26) ^ |
Monocytes, ×109 | 0.58 (0.39;0.71) | 0.51 (0.29;0.58) | 0.38 (0.24;0.51) ^ |
Neutrophils, ×109 | 2.96 (2.78;4.31) | 3.53 (1.98;4.65) | 3.06 (2.31;3.97) |
Eosinophils, ×109 | 0.11 (0.08;0.23) * | 0.02 (0.01;0.03) ^ | 0.01 (0;0.04) ^ |
Basophils, ×109 | 0.08 (0.06;1.00) * | 0.03 (0.02;0.04) ^ | 0.01 (0.01;0.04) ^ |
* p < 0.01, compared severe and moderate COVID-19. ^ p < 0.01, compared with HD.