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. 2021 Oct 15;22(20):11134. doi: 10.3390/ijms222011134

Figure 5.

Figure 5

Evolution of DPF-containing proteins. Originally, PHF10 and the gene ancestral to DPF13 and MOZ/MORF groups diverged from the common ancestor. Afterwards, the latter group multiplied to five members. Most likely, PHD duplication occurred in the very last eukaryotic common ancestor, since the DPF domain is present in all these genes.