Table 3.
Models for predicting failure of liberation from oxygen therapy at day 28 following hospital admission through the top nine performing biomarkers.
| AUC (95% CI) | p | |
|---|---|---|
| qSOFA score | 0.73 (0.59–0.87) | 0.005 |
| SpO2/FiO2 | 0.74 (0.60–0.88) | 0.004 |
| Procalcitonin | 0.73 (0.57–0.88) | 0.01 |
| D-dimer | 0.70 (0.54–0.85) | 0.02 |
| Ang-2 | 0.70 (0.54–0.86) | 0.02 |
| Ang-2/Ang-1 | 0.71 (0.56–0.86) | 0.01 |
| Endocan (day 4–baseline) | 0.75 (0.60–0.90) | 0.003 |
| Endocan (day 7–baseline) | 0.81 (0.67–0.94) | <0.001 |
| TNF-α | 0.73 (0.60–0.87) | 0.006 |
Ang-1: angiopoietin-1; Ang-2: angiopoietin-2; AUC: area under the curve; CI: confidence interval; FiO2: fraction of inspired oxygen; SpO2: pulse oximetric saturation; qSOFA: quick Sequential Organ Failure Assessment; TNF-α: tumor necrosis factor-α.