Table 1.
Demographic characteristics, clinical biomarkers values, and results from logistic regression.
| Study Population, n = 58 | Control Group, n = 34, HFrEF | Study Group, n = 24, HFpEF | p Value | |
|---|---|---|---|---|
| Median (1°–3° Quartile), | ||||
| Age, years | All= 68 (59–79) F = 75 (67–82) M = 67 (55–78) |
69 (59–78) | 74 (60–82) | |
| Gender, n (%) | F = 18 (32) M = 40 (68) |
7 (21) 27 (79) |
11 (50) 13 (50) |
0.321 |
| LVEF, % | 40 (30–50) | 30 (23–37) | 60 (50–60) | NA |
| Urea, mmol/L | 8.3 (6.55–12) | 8.75 (6.75–12) | 7.6 (6–10) | 0.553 |
| Creatinine, µmol/L | 101(87–130) | 105 (95–139) | 87 (75–104) | 0.663 |
| eGFR, mL/min–1,73 m2 | 61 (45–78) | 56 (41–77) | 65 (47–81) | 0.779 |
| NT-proBNP, pg/mL | 1457 (465–3675) | 1546 (491–4092) | 1090 (460–2803) | 0.237 |
| hs-cTnT | 33 (16–48) | 33 (27–48) | 27 (11–45) | 0.488 |
| CRP, mg/L | 2.6 (1–6) | 2.4 (1–4.3) | 5 (1–8.6) | 0.485 |
| sST2, ng/mL | 33.4 (24–56) | 32.0 (22–52) | 44 (25–64) | 0.256 |
| Ferritin, µg/L | 146 (87–296) | 154 (122–338) | 138 (60–183) | 0.526 |
| TSC, % | 21.0 (16–28) | 25.0 (18–29) | 17 (13–24) | 0.232 |
HFrEF: heart failure with reduced ejection fraction; HFpEF: heart failure with preserved ejection fraction; F: female, M: male; LVEF: left ventricular ejection fraction; eGFR: estimated glomerular filtration rate; NT-proBNP: N-terminal pro–B-type natriuretic peptide; hs-cTnT: high-sensitive cardiac troponin T; CRP: C—reactive protein; sST2: soluble suppression of tumorigenesis-2; TSC: transferrin saturation coefficient.