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. Author manuscript; available in PMC: 2021 Oct 23.
Published in final edited form as: Dev Dyn. 2014 Sep 22;244(1):56–68. doi: 10.1002/dvdy.24178

Fig. 4. Enteric vascular remodeling is correlated with recruitment of mural cells to intestinal arteries and vasa recta.

Fig. 4.

A: At E12.5, the onset of vascular remodeling, the submucosal vascular plexus is connected to the mesenteric vasculature by capillaries without detectable pericyte and vascular smooth muscle cell (VSMC) coverage. B-C: As these capillaries remodel to form vasa recta (arrows), NG2+ mural cells are recruited to these large-diameter arteries. The submucosal vascular plexus remains largely free of coverage at E15.5. D-F: In the mesentery, αSMA+ and/or NG2+ mural cells first appear adjacent to the SMA at E12.5. As mesenteric capillaries remodel to form intestinal arteries and veins between E13.5 and E15.5, mural cells selectively surround arteries (arrows) but not veins (open arrowheads). Scale bars = 100 μm.