Table 1.
Serum AST, ALT, and ALP activities in the mice fed with the liquid Lieber–DeCarli ethanol diet.
Groups | AST (U/L) | ALT (U/L) | ALP (IU/L) |
---|---|---|---|
NOR | 44.9 ± 4.9 * | 17.3 ± 2.5 ** | 67.0 ± 3.1 ** |
EtOH | 51.0 ± 9.8 | 22.1 ± 6.2 | 76.0 ± 5.5 |
SL | 43.0 ± 4.7 ** | 18.5 ± 2.4 * | 73.3 ± 5.9 |
MS-L | 41.6 ± 3.7 ** | 16.8 ± 2.7 ** | 70.6 ± 4.1 |
MS-H | 39.5 ± 3.4 *** | 16.3 ± 1.9 ** | 68.6 ± 6.1 * |
AK-L | 42.1 ± 4.3 ** | 17.0 ± 2.8 ** | 68.1 ± 4.3 ** |
AK-H | 38.9 ± 3.2 *** | 16.8 ± 0.5 ** | 69.5 ± 6.7 * |
Two groups of the mice were fed a normal diet (NOR group) or a liquid Lieber—DeCarli ethanol diet (EtOH group) without the administration of test materials. The other ethanol-induced liver injury mice were administered silymarin (200 mg/kg bw/day), a low dose of monascin (0.615 mg/kg bw/day; MS-L group), a high dose of monascin (3.075 mg/kg bw/day; MS-H group), ankaflavin (0.3075 mg/kg bw/day; AK-L group), or a high dose of ankaflavin (1.5375 mg/kg bw day; AK-H group). Data are presented as mean ± SD (n = 8). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. EtOH group.