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. 2021 Oct 18;26(20):6301. doi: 10.3390/molecules26206301

Table 1.

Serum AST, ALT, and ALP activities in the mice fed with the liquid Lieber–DeCarli ethanol diet.

Groups AST (U/L) ALT (U/L) ALP (IU/L)
NOR 44.9 ± 4.9 * 17.3 ± 2.5 ** 67.0 ± 3.1 **
EtOH 51.0 ± 9.8 22.1 ± 6.2 76.0 ± 5.5
SL 43.0 ± 4.7 ** 18.5 ± 2.4 * 73.3 ± 5.9
MS-L 41.6 ± 3.7 ** 16.8 ± 2.7 ** 70.6 ± 4.1
MS-H 39.5 ± 3.4 *** 16.3 ± 1.9 ** 68.6 ± 6.1 *
AK-L 42.1 ± 4.3 ** 17.0 ± 2.8 ** 68.1 ± 4.3 **
AK-H 38.9 ± 3.2 *** 16.8 ± 0.5 ** 69.5 ± 6.7 *

Two groups of the mice were fed a normal diet (NOR group) or a liquid Lieber—DeCarli ethanol diet (EtOH group) without the administration of test materials. The other ethanol-induced liver injury mice were administered silymarin (200 mg/kg bw/day), a low dose of monascin (0.615 mg/kg bw/day; MS-L group), a high dose of monascin (3.075 mg/kg bw/day; MS-H group), ankaflavin (0.3075 mg/kg bw/day; AK-L group), or a high dose of ankaflavin (1.5375 mg/kg bw day; AK-H group). Data are presented as mean ± SD (n = 8). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. EtOH group.