Table 2.
Serum or hepatic triglyceride and cholesterol levels in the mice fed with the liquid Lieber–DeCarli ethanol diet.
| Groups | Serum | Liver | ||
|---|---|---|---|---|
| TC (mg/dL) | TG (mg/dL) | TC (mg/g) | TG (mg/g) | |
| NOR | 65.62 ± 4.73 | 99.61 ± 10.39 ** | 3.41 ± 0.05 *** | 3.10 ± 0.56 *** |
| EtOH | 68.82 ± 10.40 | 119.61 ± 14.32 | 3.77 ± 0.16 | 4.86 ± 0.84 |
| SL | 63.74 ± 5.11 | 110.33 ± 8.78 * | 3.43 ± 0.14 *** | 3.01 ± 0.39 *** |
| MS-L | 58.35 ± 7.39 * | 94.85 ± 10.50 ** | 3.43 ± 0.11 *** | 2.95 ± 0.38 *** |
| MS-H | 60.72 ± 7.09 * | 88.45 ± 4.89 *** | 3.19 ± 0.08 *** | 2.52 ± 0.21 *** |
| AK-L | 59.32 ± 4.45 * | 106.48 ± 8.48 * | 3.22 ± 0.15 *** | 2.85 ± 0.53 *** |
| AK-H | 60.49 ± 5.72 * | 96.88 ± 9.56 ** | 3.10 ± 0.09 *** | 2.44 ± 0.18 *** |
Two groups of the mice were fed a normal diet (NOR group) or a liquid Lieber—DeCarli ethanol diet (EtOH group) without the administration of test materials. The other ethanol-induced liver injury mice were administered silymarin (200 mg/kg bw/day), a low dose of monascin (0.615 mg/kg bw/day; MS-L group), a high dose of monascin (3.075 mg/kg bw/day; MS-H group), ankaflavin (0.3075 mg/kg bw/day; AK-L group), or a high dose of ankaflavin (1.5375 mg/kg bw day; AK-H group). Data are presented as mean ± SD (n = 8). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. EtOH group. Abbreviations: TC, total cholesterol and TG, triglyceride.