Table 3.

Antioxidant enzyme activities in the mice fed with the liquid Lieber–DeCarli ethanol diet.

Groups	CAT Activity (U/mg Protein)	SOD Activity (U/mg Protein)	GPx Activity (U/mg Protein)	GRd Activity (U/mg Protein)
NOR	0.54 ± 0.06 ***	4.43 ± 0.65 ***	807.02 ± 60.02 ***	68.67 ± 6.02 ***
EtOH	0.42 ± 0.07	2.59 ± 0.23	611.87 ± 53.06	57.76 ± 3.84
SL	0.43 ± 0.08	3.55 ± 0.52 **	666.49 ± 52.95	65.11 ± 4.25 **
MS-L	0.62 ± 0.03 ***	3.12 ± 0.35	604.53 ± 64.00	63.31 ± 5.92 *
MS-H	0.56 ± 0.06 ***	3.60 ± 0.61 **	678.79 ± 52.78 *	71.39 ± 4.82 ***
AK-L	0.54 ± 0.04 ***	3.36 ± 0.63 **	653.51 ± 37.76	66.05 ± 7.38 **
AK-H	0.58 ± 0.07 ***	3.82 ± 0.68 ***	685.66 ± 71.14 *	73.18 ± 3.35 ***

Two groups of the mice were fed a normal diet (NOR group) or a liquid Lieber–DeCarli ethanol diet (EtOH group) without the administration of test materials. The other ethanol-induced liver injury mice were administered silymarin (200 mg/kg bw/day), a low dose of monascin (0.615 mg/kg bw/day; MS-L group), a high dose of monascin (3.075 mg/kg bw/day; MS-H group), ankaflavin (0.3075 mg/kg bw/day; AK-L group), or a high dose of ankaflavin (1.5375 mg/kg bw day; AK-H group). Data are presented as mean ± SD (n = 8). * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. EtOH group. Abbreviations: GPx, glutathione peroxidase; GRd, glutathione reductase; CAT, catalase; and SOD, superoxide dismutase.