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. 2021 Jul 3;24(10):759–775. doi: 10.1093/ijnp/pyab037

Table 2.

Selection of Findings From Induced Neurons for Psychiatric Disorders

Disorder Model Results Reference
Neurodegenerative disorders
Parkinson’s disease iDA Successful induction of functional dopaminergic neurons from human fibroblasts as a model for Parkinson’s disease (Caiazzo et al., 2011)
Neurodevelopmental disorders
ASD iPSC-iNs Transdifferentiation prevents manifestation of ASD-associated phenotypes (Schafer et al., 2019)

Abbreviations: ASD, autism spectrum disorder; iDA, induced dopaminergic neurons; iNs, induced neurons; iPSC, induced pluripotent stem cells.