Table 2.
Disorder | Model | Results | Reference |
---|---|---|---|
Neurodegenerative disorders | |||
Parkinson’s disease | iDA | Successful induction of functional dopaminergic neurons from human fibroblasts as a model for Parkinson’s disease | (Caiazzo et al., 2011) |
Neurodevelopmental disorders | |||
ASD | iPSC-iNs | Transdifferentiation prevents manifestation of ASD-associated phenotypes | (Schafer et al., 2019) |
Abbreviations: ASD, autism spectrum disorder; iDA, induced dopaminergic neurons; iNs, induced neurons; iPSC, induced pluripotent stem cells.