TABLE 1.

MICs for 105 S. pneumoniae isolates with reduced susceptibility to penicillin (penicillin MIC ≥ 0.12 μg/ml)

Drug	MIC50a (μg/ml)	MIC90a (μg/ml)	MIC range (μg/ml)
Penicillin	1.0	2.0	0.25–2.0
Cefotaxime	1.0	1.0	0.12–2.0
Erythromycin	8.0	≥64	0.12–>64
Trimethoprim	≥64	≥64	2.0–>64
Chloramphenicol	16	16	2.0–16
Tetracycline	16	32	0.25–>64

^aMIC₅₀ and MIC₉₀, MICs at which 50 and 90%, respectively, are inhibited.