TABLE 2.
Relationship of penicillin susceptibility category to cefotaxime susceptibility and multidrug resistance in 105 S. pneumoniae isolates with penicillin MICs of ≥ 0.12 μg/ml
| Resistance typea | No. of isolates (%)
|
||
|---|---|---|---|
| Penicillin intermediateb | Penicillin resistantc | Totald | |
| Cefotaxime I (MIC, 1.0 μg/ml) | 53 (80) | 35 (90) | 88 (84) |
| Cefotaxime R (MIC, ≥2.0 μg/ml) | 2 (3) | 4 (10) | 6 (6) |
| MDR | 48 (73) | 34 (87) | 82 (78) |
| MDR plus cefotaxime I or R | 41 (62) | 34 (87) | 75 (71) |
a
I, intermediate; R, resistant; MDR, multidrug resistant (MICs of tetracycline, erythromycin, chloramphenicol, and trimethoprim of ≥4.0, ≥0.5, ≥8.0, and ≥1.0 μg/ml, respectively).
b
MIC, 0.1 to 1.0 μg/ml; n = 66.
c
MIC, ≥2.0 μg/ml; n = 39.
d
n = 105.