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. 2021 Oct 12;11(10):1020. doi: 10.3390/jpm11101020

Table 1.

Demographic, clinical, and hormone variables for admission, discharge, and 3 months post-discharge.

Variables Admission
(Time 1)
Discharge
(Time 2)
3 Months Post-Discharge (Time 3)
Mean SD N Mean SD N Mean SD N χ2 † p Post hoc
Demographics
Age (year) 29.9 13.7 73 - - - - - - - - -
Age of onset (year) 17.8 7.2 72 - - - - - - - - -
BMI (kg/m2) 15.1 1.8 73 17.1 1.5 71 17.9 2.4 49 59.3 <0.01 T2 > T1 **
T3 > T1 **
T3 > T2 **
% IBW 68.8 7.8 73 79.5 5.7 71 83.5 10.9 49 67.8 <0.01 T2 > T1 **
T3 > T1 **
T3 > T2 **
Psychological factors
Anxiety 25.1 13.3 67 18.6 11.7 64 17.7 11.1 50 16.9 <0.01 T1 > T2 **
T1 > T3 **
Depression 32.9 15.7 65 22.1 16.5 63 21.6 15.3 49 17.8 <0.01 T1 > T2 **
T1 > T3 **
Binge-eating
OBE episode 13.9 52.6 72 4.3 13.0 73 2.4 5.9 73 6.8 0.03 T1 > T3 **
SBE episode 16.7 39.6 73 9.0 18.8 73 4.5 8.0 73 20.3 <0.01 T1 > T2 *
T1 > T3 **
Hormones
Cortisol (ug/dL) 19.9 6.4 55 19.1 7.1 51 14.8 6.4 24 6.3 0.04 T1 > T3 **
T2 > T3 *
ACTH (pg/mL) 84.0 25.8 55 89.2 28.4 51 74.8 25.4 24 4.9 0.09 -
NE (pg/mL) 414.0 311.5 51 349.0 276.4 48 567.6 462.8 22 1.7 0.43 -
Ghrelin active (pg/mL) 216.5 104.0 68 192.9 75.5 60 273.6 184.2 28 1.7 0.44 -
Ghrelin total (pg/mL) 2153.0 1151.1 69 1360.6 558.8 61 1972.5 856.1 29 7.5 0.02 T1 > T2 **
T3 > T2 *
Leptin (ng/mL) 8.4 5.7 53 15.3 13.4 45 21.1 18.3 17 8.1 0.02 T2 > T1 **
T3 > T1 *

Note. BMI = body mass index; % IBW = the percentage of ideal body weight; OBE = Objective binge-eating episode during the past four weeks; SBE = Subjective binge-eating episode during the past four weeks; SD = standard deviation; ACTH = adrenocorticotropic hormone; NE = norepinephrine; Anxiety = sum score of the Beck Anxiety Inventory; Depression = sum score of the Beck Depression Inventory-II; ** p < 0.01; * p < 0.05; Repeated-measures ANOVA on ranks; Wilcoxon Signed Rank Test with Bonferroni adjustment.