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. 2021 Oct 19;22(20):11259. doi: 10.3390/ijms222011259

Figure 4.

Figure 4

ERK5 is required for HH-GLI-dependent melanoma cell proliferation. (A,B) Growth curves of viable melanoma cells transduced with the indicated lentiviral vectors. Data shown are mean ± SD of one representative experiment out of three performed in triplicate. * p < 0.05, ** p < 0.01, *** p < 0.001 as determined by Student’s t-test. (C,D) In the same experiments shown in (A,B), cell cycle phase distribution (propidium iodide staining) was estimated by flow cytometry. * p < 0.05, ** p < 0.01, *** p < 0.001 versus pLV/shNT; # p < 0.05, ## p < 0.01, ### p < 0.001 versus shPTCH1/shNT.