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Comparison of the conserved CATC of HSV-1 and the betaherpesvirus-specific CATC of HCMV. (a) The structure of the HSV-1 CATC (UL17, UL25, and UL36) (PDB: 6CGR). The inset shows a closeup of the HSV-1 CATC helical bundle along with corresponding locations of N and C termini in each protein. (b) The structure of the HCMV CATC protein pp150 (PDB: 5VKU); Structures were visualized using PyMOL [88].
