Table 4.
In silico acute rodent toxicity assays for antrocin.
| LD50 | |||
| Administration Route | Log10(mmol/kg) | mg/kg | OECD classification |
| Intraperitoneal (i.p) | 0.421 | 618 | Class 5 |
| Intravenous (i.v) | −0.955 | 26 | Class 3 |
| Oral gavage (o.p) | 1.536 | 804.3 | Non-toxic |
| Subcutaneous (s.c) | 0.344 | 517.3 | Class 4 |
| Environmental Toxicity | |||
| Bioaccumulation factor Log10(BCF) | 1.521 | ||
| Daphnia magna LC50-Log10(mol/L) | 4.594 | ||
| Fathead Minnow LC50 Log10(mmol/L) | −1.648 | ||
| Tetrahymena pyriformis IGC50-Log10(mol/L) | 0.856 | ||
The toxicity classification was based on the acute rodent toxicity chemical classification by the OECD Project. LD50, 50% lethal dose.