Depth-dependent electrophysiological measures. (A) Proportion of active microelectrodes for upper (violet), middle (red), and lower (green) microelectrodes located in the SS arrays. The annotation a denotes significant differences between upper and middle groups, b denotes significant differences between upper and lower groups, and c denotes significant differences between middle and lower groups, respectively (test of proportions z-test, p < 0.05). (B) Noise levels for the microelectrodes at different depths. The annotation d indicates significant differences during Week 2 and Week 4 between upper third and multi-shank microelectrodes. Data presented as the mean ± SEM.