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. 2021 Oct 16;11(10):787. doi: 10.3390/membranes11100787

Figure 3.

Figure 3

The hypothesis of the first step of the mechanism for SMS enzyme. The reaction starts with a nucleophilic attack of the hydroxyl group of a tyrosine in the binding site to the phosphorus atom of a PC molecule. The result is the formation of DAG and phosphorylation of the enzyme.