Table 3.
Residual drug post nebulisation within the VMN and JN devices and the pMDI adapters during active and passive humidification (STD = standard). Results are presented as mean ± SD % residual drug.
| Device Type | Humidification Type |
Ventilation Type | Mean ± SD (% Residual Drug) |
p-Value |
|---|---|---|---|---|
| VMN | ACTIVE | STD | 0.05 ± 0.08 | 0.5447 |
| PASSIVE | 0.02 ± 0.03 | |||
| ACTIVE | LTV | 0.01 ± 0.03 | 0.3589 | |
| JN | ACTIVE | STD | 57.12 ± 3.83 | 0.0741 |
| PASSIVE | 63.46 ± 5.75 | |||
| ACTIVE | LTV | 56.15 ± 12.20 | 0.8695 | |
| CombiHaler | ACTIVE | STD | 56.46 ± 9.38 | 0.1333 |
| LTV | 65.38 ± 7.40 | |||
| F&P Wye | ACTIVE | STD | 64.46 ± 6.08 | 0.6585 |
| LTV | 63.00 ± 3.70 | |||
| MiniSpacer | ACTIVE | STD | 29.38 ± 2.35 | <0.0001 |
| PASSIVE | 18.46 ± 1.28 | |||
| ACTIVE | LTV | 17.23 ± 5.93 | 0.0028 |