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. 2021 Oct 18;26(20):6302. doi: 10.3390/molecules26206302

Figure 3.

Figure 3

ACHN cell migration measured using a scratch assay at t = 0 h and t = 72 h of treatment using either DMC (10.94 µM) or EF24 (21.36 µM) in combination with TRAIL. (a) Scratch area (edges marked in red) at 0 and 72 h after treatment with DMC in combination with TRAIL and EF24 in combination with TRAIL. (b) ACHN cell migration decreases in presence of DMC and EF24 both individually and in combination with TRAIL. Combination treatment of DMC and TRAIL reduces scratch width to 54.11% after 72 h, whereas control cells reduce scratch width to 28.78%. Treatment with EF24 in combination with TRAIL reduces scratch width to 53.05%. Results shown are an average of 4 independent experiments. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. Images analyzed using ImageJ [34].