Table 2.

Values of experimentally determined sulfamethizole solubility in five studied aqueous organic solvents binary mixtures. The first column comprises mole fractions of organic solvent in solute free solutions. (x₂* represents the mole fraction of organic solvent in solute-free binary solution).

x2*	298.15 K	303.15 K	313.15 K	313.15 K
1,4-Dioxane + water, xSMT × 104
0.0	0.34 ± 0.01	0.41 ± 0.02	0.48 ± 0.01	0.58 ± 0.02
0.2	36.00 ± 1.06	40.20 ± 1.61	43.88 ± 2.51	49.37 ± 2.90
0.4	69.74 ± 2.14	79.01 ± 2.74	89.97 ± 2.50	103.25 ± 2.35
0.6	74.69 ± 3.14	86.23 ± 2.56	99.46 ± 3.01	115.37 ± 3.04
0.8	47.15 ± 1.50	52.31 ± 1.66	57.73 ± 2.33	64.57 ± 2.94
1.0	10.03 ± 0.32	10.79 ± 0.39	11.63 ± 0.64	12.49 ± 0.57
Methanol + water, xSMT × 104
0.2	2.12 ± 0.13	2.57 ± 0.14	3.06 ± 0.12	3.69 ±0.23
0.4	8.58 ± 0.43	9.50 ± 0.38	10.36 ± 0.48	11.50 ± 0.58
0.6	21.88 ± 0.68	23.29 ± 0.68	24.86 ± 0.56	26.53 ± 0.57
0.8	33.36 ± 0.68	35.54 ± 0.82	37.89 ± 0.78	40.62 ± 1.12
1.0	38.72 ± 0.91	41.10 ± 1.35	43.68 ± 1.30	46.70 ± 1.20
DMF + water, xSMT × 102
0.2	3.99 ± 0.21	4.99 ± 0.26	6.19 ± 0.21	7.68± 0.17
0.4	8.04 ± 0.57	11.13 ± 0.36	14.31 ± 0.19	18.16 ± 0.98
0.6	12.37 ± 0.78	17.57 ± 0.68	22.71 ± 0.99	28.58 ± 0.61
0.8	17.22 ± 0.82	23.45 ± 0.64	30.53 ± 0.98	37.94 ± 0.48
1.0	22.69 ± 0.87	29.91 ± 1.02	38.05 ± 0.86	46.50 ± 1.16
DMSO + water, xSMT × 102
0.2	0.45 ± 0.02	0.81 ± 0.04	1.31 ± 0.04	1.89 ± 0.02
0.4	1.08 ± 0.05	2.41 ± 0.14	3.69 ± 0.15	5.22 ± 0.20
0.6	3.40 ± 0.16	4.98 ± 0.03	6.89 ± 0.25	9.32 ± 0.23
0.8	7.89 ± 0.34	10.16 ± 0.55	12.98 ± 0.69	16.54 ± 0.57
1.0	17.97 ± 0.66	21.05 ± 0.57	24.81 ± 0.10	29.30 ± 0.60
Acetonitrile + water, xSMT × 103
0.2	3.24 ± 0.18	3.62 ± 0.10	4.03 ± 0.14	4.54 ± 0.17
0.4	9.02 ± 0.39	10.05 ± 0.23	11.22 ± 0.29	12.51 ± 0.38
0.6	12.04 ± 0.24	13.29 ± 0.36	14.62 ± 0.39	16.16 ± 0.18
0.8	6.92 ± 0.26	7.89 ± 0.37	8.91 ± 0.41	10.05 ± 0.43
1.0	2.83 ± 0.08	3.04 ± 0.07	3.21 ± 0.09	3.43 ± 0.08