Table 1.
Analytical performance of the MVD Histoplasma urinary Ag LFA and MVD EIA.
MVD LFA | MVD EIA | |||||||
---|---|---|---|---|---|---|---|---|
Culture | Culture | |||||||
LFA | + | − | EIA | + | − | |||
+ | 25 | 3 | + | 25 | 17 | |||
− | 1 | 71 | − | 1 | 57 | |||
% (CI 95%) | ||||||||
Sensitivity | 96% (80–100) | 96% (80–100) | ||||||
Specificity | 96% (89–99) | 77% (66–86) | ||||||
Accuracy | 96% (90–99) | 82% (73–89) | ||||||
Positive predictive value | 89% (73–96) | 60% (49–69) | ||||||
Negative predictive value | 99% (91–100) | 98% (89–100) | ||||||
Kappa | 0.656 (0.509–0.803) |
(LFA) Lateral flow assay; (EIA) Enzyme Immunoassay; (95% CI confidence interval); (+) positive result; (−) negative result.