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. 2021 Oct 17;11(10):1042. doi: 10.3390/jpm11101042

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Tracers developed for functional imaging of NETs. Legend: neuroendocrine tumour cell (NET CELL); ⁶⁸Ga-NOTA-MAL-Cys39-exendin-4 (⁶⁸Ga NMC39); glucagon-like peptide-1 receptor (GLP-1R); ¹²³I metaiodobenzylguanidine (¹²³I MIBG); norepinephrine transporter (NE); ^99mTc labelled SA: ^99mTc-EDDA-hydrazinonicotinyl-Tyr3-octreotate (^99mTc-HYNIC-TATE) and ^99mTc-EDDA-hydrazinonicotinyl-Tyr3-octreotide (^99mTc-EDDA/HYNIC-TOC; ^99mTc-TOC); ¹¹¹In-diethylenetriaminepentaacetic acid-D-Phe1-octreotide (¹¹¹In -DTPA-octreotide); ⁶⁸Ga-labelled somatostatin analogs: ⁶⁸Ga-DOTA-Phe1-Tyr3-Octreotide (DOTATOC), ⁶⁸Ga-DOTA-Nal3 -Octreotide (DOTANOC), and ⁶⁸Ga-DOTA-Tyr3-Octreotate (DOTATATE); somatostatin receptors (SST); ⁶⁴Cu-DOTA-TATE (⁶⁴Cu-TATE); ¹¹C-5-hydroxytryptophan (¹¹C-5HTP); L-type amino acid transporter (LAT); 6-Fluoro-(¹⁸F)-l-3,4-dihydroxyphenylalanine (¹⁸F-DOPA); L-[methyl-¹¹C]-methionine (¹¹C-MET); ¹⁸F-2-fluoro-2-deoxy-D-glucose (¹⁸FDG); glucose transporters (Glut).