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. 2021 Oct 14;10(10):2183. doi: 10.3390/plants10102183

Figure 2.

Figure 2

Primary inhibition test using HST and HSD as inhibitor molecules against flavivirus proteases. DENV2, YFV, and WNV NS2B/NS3pro enzymatic activity [%]. Final concentration of the compound was set to 10 µM. HST inhibited the proteases activity between 55% and 80%. Contrary to this, HSD inhibited the proteases activity by about 30%. The data shown are the mean ± SD from 3 independent measurements (n = 3). Asterisks mean that the data differs from the control (0 µM inhibitor) significantly at p < 0.01 (**) and p < 0.001 (***), level according to ANOVA and Tukey’s test.