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. 2021 Oct 14;10(10):2183. doi: 10.3390/plants10102183

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Normalized activity, inhibition effect and inhibition mode of HST over DENV2, YFV, and WNV NS2B/NS3^pro. Lineweaver-Burk plots were used to determine the inhibition modes. [S] is the substrate concentration; v is the initial reaction rate. Inhibition of DENV2, YFV, and WNV NS2B/NS3^pro by HST are shown in (A,C,E), respectively. Lineweaver-Burk plots for HST inhibition of DENV2, YFV, and WNV NS2B/NS3^pro are shown in (B,D,F), respectively. Data shown are the mean ± SD from 3 independent measurements (n = 3).