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. 2021 Oct 15;13(10):1698. doi: 10.3390/pharmaceutics13101698

Table 5.

Ocular tolerance: in vitro (HET-CAM) and in vivo (Draize test).

Formulation Medium Score Classification
HET-CAM Draize
bLF-LIP 0.07 ± 0.00 0.00 ± 0.00 Non-irritant
Free bLF (20 mg·mL−1) 0.07 ± 0.00 0.00 ± 0.00 Non-irritant