Table 2.
Clinical profiles, viral load, and mRNA expression of HPV-11-infected papillomas.
| Clinicopathological Characteristics | DNA Viral Load |
HPV mRNA Expression/β-Actin | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Age (Years) | Sex | Surgery | Number of Tumors | Subsite | Derkay Score | (Copies/ ng DNA) |
E6 | E7 | E1 | E2 | E4 | E5a | E5b | L2 | L1 |
| 1 | 44 | M | 1st | multiple | Bil TVC | 5 | 64,192 | 0.11588 | 0.10541 | 0.23529 | 0.39033 | 3.95554 | 0.98977 | 2.33520 | 0.03630 | 0.02664 |
| 2 | 44 | M | 1st | multiple | Bil TVC | 7 | 226,916 | 0.38194 | 1.95009 | 6.36798 | 10.67637 | 56.84702 | 16.06985 | 39.08463 | 0.32797 | 0.11461 |
| 3 | 5 | M | 13th | multiple | E | 5 | 84 | 0.00316 | 0.06096 | 0.01683 | 0.02952 | 0.43326 | 0.20933 | 0.54957 | 0.00101 | 0.00059 |
| 5 | multiple | PW | 3 | 642,111 | 0.02153 | 0.04717 | 0.04567 | 0.09687 | 0.87938 | 0.20339 | 0.49420 | 0.00542 | 0.00482 | |||
| 5 | 14th | multiple | Bil TVC | 4 | 230,366 | 0.03669 | 0.03956 | 0.08475 | 0.13412 | 1.45394 | 0.36106 | 0.85643 | 0.00581 | 0.00167 | ||
| 6 | 15th | multiple | Bil TVC | 5 | 33,153 | 0.02311 | 0.55589 | 0.03616 | 0.12762 | 0.83358 | 0.89123 | 5.44958 | 0.00210 | 0.00170 | ||
| 7 | 16th | multiple | E | 2 | 15,711 | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||
| 7 | multiple | Bil TVC | 4 | 601,070 | 0.04394 | 0.20269 | 0.03255 | 0.15081 | 1.16959 | 0.80580 | 1.18013 | 0.00918 | 0.00594 | |||
| 7 | multiple | PW | 2 | 71,468 | 0.18674 | 0.62598 | 0.11146 | 0.35295 | 4.58308 | 4.86911 | 5.82166 | 0.04036 | 0.06345 | |||
| 4 | 44 | F | 1st | multiple | NP | - | 11,346 | 0.17928 | 0.67253 | 0.08880 | 0.41194 | 3.45012 | 3.11286 | 4.59908 | 0.00536 | 0.00490 |
| 5 | 63 | M | 1st | multiple | NS | - | 246,077 | 0.17783 | 0.77629 | 0.47749 | 0.41261 | 4.80617 | 1.05967 | 2.48394 | 0.13504 | 0.10001 |
Bil, bilateral; E, epiglottis; F, female; M, male; NA, not available; NP, nasopharynx; NS, nasal septum; PW, posterior wall of the hypopharynx; TVC, true vocal cord.