Table 3.
Limits of detection (LOD) and limit of quantification (LOQ) of three nitrosamine analytical methods.
| Nitrosamines | LOD (µg/L) | LOQ (µg/L) | ||||
|---|---|---|---|---|---|---|
| GC-MS/MS | APCI-LC-MS/MS | ESI-LC-MS/MS | GC-MS/MS | APCI-LC-MS/MS | ESI-LC-MS/MS | |
| NDMA | 0.12 | 62.5 | 62.5 | 0.24 | 125 | 125 |
| NDEA | 0.24 | 0.48 | 7.81 | 0.48 | 0.96 | 15.62 |
| NDPA | 0.24 | 0.98 | 7.81 | 0.48 | 1.96 | 15.62 |
| NDBA | 0.12 | 0.49 | 0.24 | 0.24 | 0.98 | 0.48 |
| NPIP | 0.12 | 0.24 | 0.48 | 0.24 | 0.48 | 0.96 |
| NPYR | 0.12 | 0.48 | 0.24 | 0.24 | 0.96 | 0.48 |
| NMOR | 0.24 | 3.12 | 0.24 | 0.48 | 6.25 | 0.48 |
| NDPhA | 0.24 | N.D. | 0.24 | 0.24 | - | 0.48 |
| NMEA | 0.48 | 3.12 | 62.5 | 0.98 | 6.25 | 125 |