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. 2021 Oct 11;22(20):10974. doi: 10.3390/ijms222010974

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Macroscopic and microscopic appearance of endometriosis in different sites. Macroscopic picture of ovarian endometrioma with fibrotic wall and a dense, dark brown content (a). Histopathological images of endometriotic implants in intestinal wall, fallopian tube, mesenteric adipose tissue, lymph node and diaphragm (b–f); m: intestinal mucosa; Ft: Fallopian tube; Ly: lymph node. The withe circles and the arrows highlight endometrial implants composed by several endometrial glands and stroma (b–f). Note the presence of hemosiderin-laden macrophages (asterisk) (f). Immunohistochemistry for CD10 shows strong expression in stroma surrounding an ectopic endometrial gland in the diaphragm (f inset). Hematoxylin and eosin stain.