Figure 2.

Magnetic resonance images from a clinically significant (A,B) and a non-clinically significant (C,D) prostate cancer lesion. Both are located in the peripheral zone; the clinically significant lesion, found in the right middle-posterior location (white arrows), appears as a nodular and well-defined area of low signal on both T2w (A) and ADC map (B). Conversely, the non-clinically significant lesion, found in the left middle-posterior location (white arrow heads), appears wedge-shaped, with no bulging on T2w (C) and only is mildly hypointense on the ADC map (D). Both lesions were deemed worthy of targeted biopsy.