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. 2021 Oct 12;14(20):6000. doi: 10.3390/ma14206000

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The viability of murine fibroblasts (L-929) after 24 h incubation with biocomposites, evaluated using MTT reduction test according to ISO-10993-5:2009. The positive control (PC) of the viability (100%) consisted of cells incubated without composites. The negative control (NC) of the viability (cells with significantly impaired metabolic activity) consisted of cells incubated with 0.3% hydrogen peroxide. The data are presented as mean ± SD, n = 6. The dashed line indicates the minimum level (70%) of the cells’ metabolic activity required to recognize the biomaterial as noncytotoxic at the in vitro level. * p values (<0.05) calculated in comparison to the NC.