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. 2021 Oct 14;26(20):6196. doi: 10.3390/molecules26206196

Table 3.

Risk of Bias Considering Aspects Reported in Section 3.

Study (I) Sample Size (II) Control Group (III) Blinded Assessment of Outcome (IV) Adequately Addressing Outcome Data (V) Standardized Sample Prep (VI) Conflict of Interest Statement Risk of Bias
Abadeh et al. [14] (2020) 2 2 2 0 0 2 moderate
Martinho et al. [16] (2015) 0 0 2 0 0 2 moderate
Yang et al. [21] (2018) 0 0 2 0 0 2 moderate
Lei et al. [22] (2020) 0 0 2 0 0 0 low
Li et al. [25] (2021) 0 0 2 0 0 0 low
Yan et al. [32] (2020) 0 0 2 0 0 0 low
Tan et al. [37] (2021) 0 1 2 0 0 0 low
Wu et al. [38] (2018) 0 0 2 0 0 2 moderate
Xie et al. [40] (2020) 0 0 2 0 0 0 low
Yan et al. [42] (2020) 0 0 2 0 1 0 low
Kang et al. [43] (2020) 0 0 2 0 0 0 low
Sharsheeva et al. [44] (2019) 0 0 2 0 0 0 low
Shen et al. [45] (2020) 0 0 2 0 0 0 low
Wen et al. [46] (2017) 0 0 2 0 0 0 low
Xu et al. [47] (2020) 0 0 2 0 0 0 low
Yan et al. [48] (2017) 0 2 2 0 1 0 moderate
Zheng et al. [49] (2020) 1 0 2 0 0 0 low
Abasian et al. [50] (2019) 0 0 2 0 0 2 moderate
Duan et al. [51] (2018) 0 2 2 0 0 0 moderate
He et al. [52] (2019) 2 0 2 0 1 0 moderate
Khatamian et al. [53] (2016) 0 0 2 0 1 2 moderate
Lv et al. [54] (2019) 0 0 2 0 1 0 low
Zhang et al. [55] (2017) 0 0 2 0 0 0 low
Zhao et al. [56] (2019) 0 0 2 0 1 0 low
Zhang et al. [57] (2019) 0 0 2 0 1 0 low
Jiang et al. [59] (2021) 0 0 2 0 0 0 low
Kulkarni et al. [60] (2021) 0 0 2 0 0 2 moderate
Pandey et al. [61] (2020) 0 0 2 0 0 0 low
Vilaca et al. [62] (2013) 0 0 2 0 0 2 moderate
Vilaca et al. [63] (2017) 0 0 2 0 0 2 moderate
Xiao et al. [64] (2020) 0 0 2 0 0 0 low
Sagir et al. [65] (2016) 0 0 2 0 0 2 moderate
Cao et al. [66] (2020) 0 0 2 0 1 0 low
Spanakis et al. [67] (2014) 2 0 2 0 0 2 moderate
Abd-Elsatar et al. [68] (2019) 0 0 2 0 0 0 low
Zheng et al. [69] (2015) 0 0 2 0 1 0 low
Tiwari et al. [70] (2017) 0 0 2 0 1 0 low
Chen et al. [71] (2020) 0 2 2 0 0 0 moderate
Xing et al. [72] (2020) 0 0 2 0 0 0 low
Salah et al. [73] (2019) 0 0 2 0 0 0 low
Zhao et al. [74] (2021) 0 0 2 0 1 0 low
Faraji Dizaji et al. [75] (2020) 0 0 2 0 0 2 moderate
Dong et al. [76] (2019) 0 2 2 0 0 2 moderate
Ettlinger et al. [77] (2019) 0 2 2 0 1 0 moderate
Jia et al. [78] (2019) 0 0 2 0 0 0 low
Kamal et al. [79] (2021) 0 0 2 0 0 0 low
Li et al. [80] (2018) 1 0 2 0 0 0 low
Qin et al. [58] (2020) 0 0 2 0 0 0 low
Zhou et al. [81] (2020) 0 0 2 0 1 0 low
Amorim et al. [82] (2012) 0 0 2 0 0 0 low
Kannen et al. [83] (2020) 2 0 2 0 0 2 moderate
Khojaewa et al. [84] (2019) 0 0 2 0 1 0 low
Tomeckova et al. [85] (2012) 0 1 2 0 1 2 moderate