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Fabrication of the AuNP-based targeted drug delivery system (TDDS) with an engineered bi-functional recombinant fusion protein TRAF(C) (TR), loaded with doxorubicin and ERBB2-siRNA (Au-TR-DX-si). It was used for further studies in vitro and in vivo. Reprinted with permission from [100]. Copyright Royal Society of Chemistry 2012.
