Table 1.
Maternal clinical features. Values presented as mean and SEM were compared using Student’s t test; values presented as ratios were analyzed using chi-square test. P-values < 0.05 indicate a significant difference. SNPs: single nucleotide polymorphisms.
| Clinical Features | Controls N = 1613 |
Preeclampsia N = 35 |
P-Value |
|---|---|---|---|
| Maternal age at delivery (year) | 29.6 ± 4.8 | 28.3 ± 6.1 | 0.232 |
| Maternal height (cm) | 163.0 ± 6.23 | 165.0 ± 6.35 | 0.108 |
| Maternal education (level) | 6.55 ± 2.47 | 6.05 ± 2.86 | 0.358 |
| BMI (before pregnancy, kg/m2) | 23.2 ± 4.6 | 25.2 ± 5.8 | 0.067 |
| Primiparity | 44 (703) | 60 (21) | 0.079 |
| Number of pregnancies | 1.35 ± 1.49 | 1.37 ± 1.77 | 0.956 |
| Number of deliveries | 0.834 ± 0.971 | 0.657 ± 0.906 | 0.261 |
| Obesity | 9(137) | 18(6) | 0.109 |
| Cigarette use (no.) | 1.48 ± 3.44 | 1.09 ± 3.37 | 0.524 |
| Maternal SNPs (% (N)) | |||
| Pro12Ala | 19.7 (333) | 26.3 (10) | 0.493 |
| C1431T | 21.3 (349) | 42.9 (15) | 0.004 |
| C681G | 39.3 (663) | 39.5 (15) | 1 |