Table 5.
NP compositions and properties. The ‘+’ sign indicates that NP exhibit the listed property, while the ‘−’ sign indicates that the property is absent. Composition is reported as mole percent.
| NP Compositions (Mole %) |
pH- Triggered Content Release |
ECM Adhesion |
HER2 Targeting |
20PC | DPPS | Cholesterol | DSPE-18PEG | DPPE-Rhodamine | PEG-DAP | HER2-Targeting Lipopeptide | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
DXR-
NP |
Responsive | + | − | + | 81 | 9 | 4.5 | 4 | 0.5 | − | 1 |
| Non-Responsive | − | − | − | 76.5 | − | 19 | 4 | 0.5 | − | − | |
| CDDP-NP | Responsive | + | + | − | 53 | 35 | 4.5 | − | 0.5 | 7 | − |
| Non-Responsive | − | − | − | 73.5 | − | 19 | 7 | 0.5 | − | − | |