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Effect of different compounds on apoptotic markers. (a) The mRNA levels of Bcl-2. (b) The mRNA levels of Bax. (c) mRNA levels of caspase-8. (d) Relative ratio of Bax/Bcl-2 mRNA. Gene expression was normalized to β-actin. The data are expressed as the mean ± SD of three rats. One-way analysis of variance (ANOVA) was used (* p < 0.05 versus saline control group, # p < 0.05 versus CCl4 group & α p < 0.05 versus DBT–CSNP-treated group).
