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. 2021 Oct 15;7(10):865. doi: 10.3390/jof7100865

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Genomic diversity of Histoplasma sp. collected from a single Research Institute in Rio de Janeiro/Brazil. (A) Unrooted Maximum Likelihood tree based on 1,470,938 SNPs indicating the existence of three genotypes: RJ, Northeast BR, and LAm B1. (B) Principal coordinate analysis (PCA) showing the population structure of H. suramericanum. The PC1 axis, which corresponds to 36% of the total genetic variation, discriminates the isolates from RJ (Southeast Brazil) and Colombia/Northeast Brazil. (C) Admixture analysis of H. suramericanum showing strong population between isolates from RJ and Colombia/Northeast. No admixture was observed between those two main groups of H. suramericanum.