Table 6.
Ref. | Vitamin D Measure | Intervention—Vitamin D Supplementation | Mental Health Outcome | Psychological Measure |
---|---|---|---|---|
[36] | 25(OH)D vitamin D level in blood FFQ |
75 µg/day vs. placebo for 12 weeks | Quality of life | Simple question (“How much has IBS affected your life?”) |
[37] | 25(OH)D vitamin D level in blood | 1250 µg/2 weeks vs. placebo for 6 months | Disease-specific quality of life | IBS-QoL |
[38] | Three 24-h dietary recalls | 1250 µg/2 weeks vs. placebo for 6 weeks | Disease-specific quality of life | IBS-QoL |
[39] | 25(OH)D vitamin D level in blood 3-days dietary recall |
1250 µg/week vs. placebo for 6 weeks | Disease-specific quality of life | IBS-QoL |
[40] | 25(OH) vitamin D level in blood 3-day dietary records |
1250 µg/week vs. placebo for 9 weeks | (1) Disease-specific quality of life (2) Anxiety and depression |
(1) IBS-QoL (2) HADS |
[41] | 25(OH) vitamin D level in blood | 75 µg/day vs. placebo for 12 weeks | Disease-specific quality of life | IBS-QoL |
25-hydroxyvitamin D (25(OH)D); FFQ—Food Frequency Questionnaire; IBS-QoL—Irritable Bowel Disease-Quality of Life questionnaire; HADS—Hospital Anxiety and Depression Scale.