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Daily BALB/c mouse body weight throughout Jazz90 and Jazz167 treatment. (a) Jazz90 and (b) Jazz167 were administered orally for 21 days at 25, 50 and 75 mg/kg. Vehicle control mice were treated with 0.5% DMSO (5 mL/kg). Points represent the mean ± S.E.M from 4-5 mice per group. Data were analysed using a two-way ANOVA coupled with a Bonferroni’s post-hoc test. None were significantly different.
