Table 3.
Risk factors for final unfavorable outcomes (death or major neurological sequelae at discharge) by univariate and multivariate analysis.
| Parameters | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p Value | Adjusted OR (95% CI) | p Value | |
| Preterm birth (GA < 37 weeks) | 2.52 (1.19–5.31) | 0.015 | 0.70 (0.24–2.08) | 0.525 |
| Septic shock | 20.7 (8.41–50.97) | <0.001 | 1.40 (0.32–6.11) | 0.654 |
| Respiratory failure (requirement of intubation) | 24.75 (10.23–59.91) | <0.001 | 14.97 (3.31–67.79) | <0.001 |
| Type III/CC-17 GBS isolates | 0.24 (0.12–0.50) | <0.001 | ||
| Type Ib/CC-12 GBS isolates | 5.92 (1.92–18.24) | 0.002 | 2.11 (0.45–9.88) | 0.344 |
| Early-onset sepsis | 3.84 (1.81–8.15) | <0.001 | 1.70 (0.70–2.42) | 0.570 |
| Leukopenia (WBC count < 5000 cells/μL) | 2.41 (1.12–5.22) | 0.025 | 0.77 (0.23–2.52) | 0.660 |
| Anemia (hemoglobin level < 11.5 mg/dL) | 1.35 (0.67–2.74) | 0.401 | ||
| Thrombocytopenia (platelet count < 150,000/μL) | 13.8 (5.65–33.68) | <0.001 | 6.19 (1.88–20.33) | 0.003 |
GA: gestational age; CSF: cerebrospinal fluid; OR: odds ratio; 95% CI: 95% confidence interval.