ADCC |
antibody-dependent cell cytotoxicity |
AIM2 |
absent in melanoma 2 |
AP-1 |
activator protein 1 |
ASC |
apoptosis-associated speck-like protein containing a CARD (caspase activation and recruitment domains) |
CCL2/MCP-1 |
monocyte chemoattractant protein-1 |
CCL4/MIP-1β |
macrophage inflammatory protein-1β |
cGAS |
cyclic GMP-AMP synthase |
DAMPs |
damage-associated molecular patterns |
DCs |
dendritic cells |
dsDNA |
double-stranded DNA |
ERK |
extracellular signal-regulated kinases |
GPI |
glycosylphosphatidylinositol |
IKK |
IκB kinase |
IRF |
IFN (interferon) regulatory factor |
IL |
interleukin |
JNK |
c-Jun N-terminal kinases |
MAPK |
mitogen-activated protein kinases |
MDA5 |
melanoma differentiation-associated gene 5 |
MHC |
major histocompatibility complex |
NF-kB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NK cells |
natural killer cells |
NLRP3 |
NOD-, LRR- and pyrin domain-containing 3 |
PAMPs |
pathogen-associated molecular patterns |
PRRs |
pathogen-recognition receptors |
STING |
stimulator of IFN genes |
TCR |
T cell receptor |
Tfh |
follicular T cell |
TGF |
transforming growth factor |
Th |
helper T cell |
TLRs |
toll-like receptors |
TNF |
tumor-necrosis factor |
TRAF6 |
tumor necrosis factor receptor-associated factor 6 |
Treg |
regulatory T cell |