Table 3.

Characteristics of the PLGA and chitosan-coated PLGA nanoparticles prepared by point prediction using response surface DOE. Particle size is the representation of the diameter of the particle (nm). Data = mean ± std (n = 3).

Emulsion Code	Particle Size (nm)	PDI	Zeta Potential (mV)	%Encapsulation Efficiency
PE1	318.23 ± 18.61	0.220 ± 0.08	−7.4 ± 2.43	64.80 ± 3.95
CS-PE1	386.67 ± 15.14	0.136 ± 0.05	+33.3 ± 4.69	57.14 ± 3.81
PE2	240.47 ± 48.75	0.084 ± 0.05	−6.9 ± 3.08	60.31± 2.46
CS-PE2	351.33 ± 27.02	0.098 ± 0.04	+31.97 ± 0.21	51.71 ± 1.82