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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Five classes of metabolites that characterize TBM: amino acids, organic acids, nucleotides, carbohydrates, and “other”. The component “pie slices” quantitatively represent each metabolite class that contributes toward the metabolic characterization of TBM.