Table 1.
Residual moisture results of the lyophilizates stored at different temperatures for the respective time.
| Configuration | Residual Moisture, % | |||||||
|---|---|---|---|---|---|---|---|---|
| 4 °C | 25 °C | 40 °C | ||||||
| 0 m | 3 m | 6 m | 1 m | 3 m | 1 m | 3 m | ||
| LMU1 | COP −A −P | 0.50 ± 0.04 | 0.88 ± 0.04 | 0.92 ± 0.03 | 0.68 ± 0.00 | 1.13 ± 0.01 | 0.68 ± 0.02 | 1.02 ± 0.03 |
| COP +A +P | 0.50 ± 0.04 | 0.78 ± 0.04 | 0.61 ± 0.02 | 0.57 ± 0.02 | 0.81 ± 0.02 | 0.66 ± 0.01 | 0.84 ± 0.01 | |
| Glass | 0.38 ± 0.08 | 0.65 ± 0.08 | 0.47 ± 0.03 | 0.48 ± 0.03 | 0.68 ± 0.02 | 0.54 ± 0.02 | 0.60 ± 0.06 | |
| 0 m | 12 m | 1 m | 3 m | 1 m | 3 m | |||
| LMU2 | COP −A −P | 1.17 ± 0.05 | 1.71 ± 0.11 | 1.24 ± 0.11 | 1.74 ± 0.07 | 1.17 ± 0.04 | 1.68 ± 0.01 | |
| COP +A +P | 1.17 ± 0.05 | 1.30 ± 0.03 | 1.26 ± 0.09 | 1.21 ± 0.03 | 1.20 ± 0.06 | 1.23 ± 0.07 | ||
| Glass | 1.03 ± 0.07 | 1.19 ± 0.15 | 1.06 ± 0.12 | 1.28 ± 0.08 | 1.20 ± 0.09 | 1.37 ± 0.03 | ||
The values are mean of three individual vials. The error represents the standard deviation of the mean. COP, cyclic olefin polymer; A, absorber; P, pouch; m, month.