Table 3.

IGF-I and IGFBP-3, lipoproteins, and carbohydrate metabolism before and after the lockdown in March–April 2020. p-values > 0.05 depicted as “NS”.

		<2 Years			2–6 Years			7–10 Years			11–17 Years			≥18 Years
		Mean	SD	p	Mean	SD	p	Mean	SD	p	Mean	SD	p	Mean	SD	p
IGF-1 (µg/L)	Pre	46.97	29.42	0.008	115.17	58.46	<0.001	233.25	74.29	0.022	307.19	109.17	NS	146.63	46.46	NS
	Post	81.73	41.63		147.61	59.31		264.11	108.65		319.13	118.17		148.63	71.97
IGFBP-3 (mg/L)	Pre	2.56	0.85	0.008	4.09	1.11	<0.001	5.51	1.00	<0.001	6.70	1.41	0.001	5.65	1.27	NS
	Post	4.13	1.18		5.01	1.16		9.01	16.39		7.41	1.72		5.88	1.19
Total cholesterol (mg/dL)	Pre	139.22	31.91	NS	163.56	28.79	NS	157.92	27.14	NS	155.52	29.45	NS	158.50	37.06	NS
	Post	150.22	17.35		167.81	27.55		164.22	21.15		156.82	27.03		159.42	37.34
Triglycerides (mg/dL)	Pre	73.56	17.07	NS	76.83	30.09	0.047	62.39	20.74	NS	77.57	37.99	0.050	88.19	54.66	NS
	Post	67.89	20.76		69.97	20.52		66.42	25.62		95.45	78.58		84.85	44.61
HDL (mg/dL)	Pre	39.81	9.02	NS	49.82	11.00	<0.001	58.23	15.12	0.008	53.14	11.11	NS	52.05	14.24	NS
	Post	45.60	8.23		55.38	9.62		63.19	11.93		53.07	11.77		52.45	12.16
LDL (mg/dL)	Pre	84.78	25.92	NS	98.80	26.99	NS	87.25	20.54	NS	88.00	23.97	NS	90.96	31.75	NS
	Post	91.11	14.13		98.58	25.90		87.72	19.86		87.05	23.75		90.92	32.47
Fasting glucose (mg/dL)	Pre	82.33	3.24	NS	81.44	9.48	NS	88.00	7.43	NS	90.44	7.56	NS	88.81	7.12	NS
	Post	80.78	8.71		85.63	12.44		89.31	8.43		91.76	7.90		96.40	32.63
OGTT 30 min (mg/dL)	Pre	127.60	17.57	NS	145.91	28.75	NS	152.47	31.19	0.035	155.14	23.70	NS	149.21	30.37	NS
	Post	134.20	33.25		149.64	27.17		165.14	28.53		158.11	26.80		158.63	34.50
OGTT 60 min (mg/dL)	Pre	112.60	28.84	NS	126.77	26.58	NS	133.61	19.87	NS	142.66	30.74	NS	139.92	42.93	0.006
	Post	124.60	43.33		129.88	31.62		137.11	32.15		148.82	36.65		157.17	41.88
OGTT 120 min (mg/dL)	Pre	111.60	32.76	NS	105.61	17.67	0.026	110.47	19.43	0.006	114.76	22.14	NS	111.76	20.44	NS
	Post	109.60	21.42		111.50	19.35		121.31	20.99		123.55	31.46		121.67	32.13
Insulin (pU/dL)	Pre	1.89	1.08	NS	4.17	3.56	NS	6.59	2.71	0.042	11.61	5.59	NS	6.99	3.39	0.003
	Post	2.42	1.70		4.24	3.05		7.79	3.79		15.34	19.21		5.12	1.76
Vitamin D (nmol/L)	Pre	92.75	66.40	NS	65.43	23.91	<0.001	74.44	48.48	NS	66.59	29.19	0.004	75.50	23.99	0.001
	Post	88.70	50.91		80.04	22.33		75.44	22.55		76.70	26.45		97.79	21.93

Abbreviations: insulin-like growth factor 1 (IGF-I), insulin-like growth factor-binding protein 3 (IGFPB-3), high-density lipoprotein (HDL), low-density lipoprotein (LDL), oral glucose tolerance test (OGTT).