Table 1.

Cox univariate and multivariate analyses to model overall survival in the CoMMpass cohort (n = 674 patients with MM) relative to the RNA-seq-based risk score, cytogenetic abnormalities.

	Univariate COX Analyses
Prognostic Variable	Proportional HR	p-Value
RNA-seq-based risk score	8.787	<0.0001
del17p	1.609	NS
1qgain	0.958	NS
t(12;14)	1.890	NS
ATR mut	1.780	NS
CREBBP mut	1.419	NS
MAP3K1 mut	0.991	NS
PMS1 mut	5.013	0.006
TP53 mut	1.162	NS