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Inhibitory effects of monacolin J and its product on HMG-CoA reductase. The inhibitory activity of monacolin J and its product (6′a-hydroxymethyl monacolin J) on HMG-CoA reductase was determined. Monacolin J and its product were used at concentrations up to 500 μM. Data are shown as the means (n = 3) ± SEM.
