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. 2021 Oct 6;13(10):1631. doi: 10.3390/pharmaceutics13101631

Figure 5.

Figure 5

Correlation between receptor expression, peptide internalization, and aggressiveness of HCC. Correlation between integrin expression and internalization of iRGD-IP followed the equation: y = b0 + b1 × log(x). White circle: non-malignant tumor or normal hepatocytes; black squares: samples from medium aggressiveness tumors; black stars: samples from high aggressiveness tumors. (A) Integrin expression and iRGD-IP internalization, (b0 = −610 ± 207, b1 = 121 ± 31) (B); NRP-1 expression and RPARPAR-IP internalization, (b0 = −1344 ± 600, b1 = 322 ± 89) (C), p32 expression and internalization of LinTT1-IP (b0 = −1456 ± 529, b1 = 294 ± 76) and TT1-IP (b0 = −1636 ± 665, b1 = 313 ± 96) (D) Correlation between score of aggressiveness and TTP-IP internalization (r = 0.479, standard error of estimate = 333.2, f = y0 + a × x with y0 = 249 ± 83, a = 69.7 ± 17).