Table 1.
Differentially upregulated lincRNAs in ovarian cancer versus normal ovary tissues a.
| NONCODE ID | Chr | Start | End | Strand | Alias | Normal Ovary | Ovarian Cancer | Fold Change b | q-Value | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean RPKM | SEM RPKM | Mean RPKM | SEM RPKM | ||||||||
| NONHSAT013448 | 10 | 54,785,023 | 54,789,855 | - | OIN1 | 3.0 | 2.6 | 79.2 | 24.8 | 26.1 | 5.6 × 10−3 |
| NONHSAT099419 | 4 | 182,443,812 | 182,444,154 | + | 3.2 | 2.7 | 40.4 | 5.5 | 12.7 | 2.9 × 10−4 | |
| NONHSAT017219 | 11 | 287,304 | 288,298 | + | 0.6 | 0.2 | 38.6 | 18.3 | 62.9 | 1.0 × 10−2 | |
| NONHSAT027397 | 12 | 26,383,751 | 26,472,653 | - | 0.5 | 0.2 | 27.4 | 11.7 | 51.5 | 1.6 × 10−3 | |
| NONHSAT015316 | 10 | 85,926,985 | 85,931,832 | - | CERNA2/HOST2 | 0.8 | 0.7 | 17.2 | 5.9 | 20.2 | 7.4 × 10−4 |
| NONHSAT032437 | 13 | 23,477,401 | 23,493,348 | + | 0.3 | 0.1 | 9.2 | 3.0 | 31.0 | 1.5 × 10−4 | |
| NONHSAT080725 | 20 | 60,880,487 | 60,881,452 | - | 0.5 | 0.2 | 8.8 | 3.8 | 19.2 | 1.3 × 10−3 | |
| NONHSAT122583 | 7 | 104,581,509 | 104,602,507 | + | 0.3 | 0.2 | 8.2 | 3.7 | 27.0 | 3.0 × 10−2 | |
| NONHSAT061517 | 19 | 15,939,789 | 15,947,064 | + | UCA1 | 0.6 | 0.5 | 6.7 | 2.0 | 11.3 | 8.1 × 10−3 |
| NONHSAT018088 | 11 | 13,002,033 | 13,005,839 | - | LINC00958 | 0.6 | 0.5 | 5.7 | 0.9 | 10.3 | 2.1 × 10−2 |
a Differentially upregulated lincRNAs in ovarian cancer were selected by the criterion described below: among transcripts mapped to NONCODE v4 gene sets, we selected 10 putative differentially expressed lincRNAs, which were particularly upregulated in ovarian cancer compared with normal tissues by ≥10-folds at an FDR q-value threshold <0.05. b Fold change of RPKM values in ovarian cancer versus normal ovary tissues. RPKM: reads per kilobase of transcript length per million mapped reads.